CDC23

Across TCGA patient cohorts, CDC23 protein abundance is significantly associated with the RNA expression of many other genes, with 7,859 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CDC23-associated genes across cancer lineages are KPNB1, TMEM97, and NDUFA8. Each is linked with CDC23 in more than 5 cancer types. Because this analysis shows association rather than direction, both CDC23-to-partner and partner-to-CDC23 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDC23 versus KPNB1 in OV, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC23→partner) and Y-score (partner→CDC23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	KPNB1 →	+0.500	+0.290	<.001	<.001	3	6
LSCC	TMEM97 →	+0.780	+0.121	<.001	<.001	3	5
OV	NDUFA8 →	+0.459	+0.197	.003	<.001	3	5
LSCC	BRCA1 →	+0.743	+0.135	<.001	<.001	3	5
UCEC	ERAL1 →	+0.490	+0.160	.004	.004	2	6
OV	PSMB7 →	+0.453	+0.173	.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,859 associations by consensus.

CDC23 vs KPNB1 — OV

Explore this scatter interactively →