CDC23

Across TCGA patient cohorts, CDC23 protein abundance is significantly associated with the protein abundance of many other proteins, with 21,369 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CDC23-associated proteins across cancer lineages are ANAPC5, CDC16, and ANAPC1. Each is linked with CDC23 in more than 9 cancer types. Because this analysis shows association rather than direction, both CDC23-to-partner and partner-to-CDC23 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDC23 versus ANAPC5 in COAD, with a Pearson correlation of 0.42.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC23→partner) and Y-score (partner→CDC23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ANAPC5 →	+0.186	+0.212	<.001	<.001	3	10
OV	CDC16 →	+0.777	+0.360	.003	.008	2	10
LSCC	ANAPC1 →	+0.204	+0.235	<.001	<.001	3	8
LSCC	DNAJC7 →	+0.294	+0.180	<.001	<.001	3	8
UCEC	GEMIN5 →	+0.285	+0.209	<.001	<.001	3	8
LSCC	AQR →	+0.296	+0.157	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,369 associations by consensus.

CDC23 vs ANAPC5 — COAD

Explore this scatter interactively →