CDC20B

Across TCGA pan-cancer cohorts, CDC20B RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of CDC20B’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where CDC20B RNA is repressed in tumor relative to normal tissue. In most cancer types CDC20B is over-expressed in tumor, although a few such as KIRP and KIRC show the opposite, repressed pattern.

KIRP, KIRC, and BRCA are the cancer types where CDC20B tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CDC20B RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	All	II,III,IV	−0.801	<.001	11	view →
KIRC	Female	All	−0.546	<.001	8	view →
BRCA	Female	All	+0.870	<.001	6	view →
LIHC	All	All	+0.096	.002	6	view →
LUSC	Female	II,III,IV	−0.304	.002	5	view →
COAD	Male	II,III,IV	+0.030	.011	3	view →
CHOL	All	All	+1.967	.023	2	view →
UCEC	All	All	+0.990	.040	2	view →
KICH	All	All	+0.839	.022	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

CDC20B–KIRP

Open the KIRP breakdown →