CDC20

Across TCGA cell cohorts, CDC20 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,497 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible CDC20-associated GO terms across cancer lineages are Nuclear chromosome segregation, Mitotic nuclear division, and Spindle checkpoint signaling. Each is linked with CDC20 in more than 19 cancer types. Because this analysis shows association rather than direction, both CDC20-to-partner and partner-to-CDC20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear chromosome segregation grouped by CDC20-low versus CDC20-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC20→partner) and Y-score (partner→CDC20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Nuclear chromosome segregation →	+0.177	+1.481	<.001	<.001	3	20
OESOPHAGUS	Mitotic nuclear division →	+0.181	+1.559	<.001	<.001	3	20
OESOPHAGUS	Spindle checkpoint signaling →	+0.205	+1.135	<.001	.001	3	20
OESOPHAGUS	Meiotic chromosome segregation →	+0.182	+1.086	.001	.009	3	20
BONE	Mitotic sister chromatid segregation →	+0.155	+1.870	.002	.001	3	20
OESOPHAGUS	Chromosome segregation →	+0.162	+1.401	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,497 associations by consensus.

Nuclear chromosome segregation by CDC20 expression — OESOPHAGUS

Explore this box plot interactively →