CDC20

Across TCGA cell cohorts, CDC20 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible CDC20-associated genes across cancer lineages are ASB17, HAO2, and KRT82. Each is linked with CDC20 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDC20-to-partner and partner-to-CDC20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASB17 grouped by CDC20-low versus CDC20-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC20→partner) and Y-score (partner→CDC20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	ASB17 →	+0.023	+5.807	<.001	.001	3	2
LUNG_NSCLC_LUAD	HAO2 →	+0.056	+3.719	<.001	.009	3	1
LUNG_NSCLC_LUAD	KRT82 →	+0.044	+4.215	<.001	.002	3	1
LUNG_NSCLC_LUAD	OOSP4B →	+0.014	+4.681	<.001	.003	3	1
LARGE_INTESTINE	GABRG1 →	+0.012	+4.196	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

ASB17 by CDC20 expression — OVARY

Explore this box plot interactively →