CDC16

Across TCGA cell cohorts, CDC16 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,203 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible CDC16-associated GO terms across cancer lineages are Ribosomal protein import into nucleus, Negative regulation of hematopoietic stem cell differentiation, and Nucleotide-excision repair, DNA gap filling. Each is linked with CDC16 in more than 15 cancer types. Because this analysis shows association rather than direction, both CDC16-to-partner and partner-to-CDC16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ribosomal protein import into nucleus grouped by CDC16-low versus CDC16-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC16→partner) and Y-score (partner→CDC16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Ribosomal protein import into nucleus →	+0.103	+0.661	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Negative regulation of hematopoietic stem cell differentiation →	+0.179	+0.874	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Nucleotide-excision repair, DNA gap filling →	+0.112	+1.060	<.001	<.001	3	12
LUNG_SCLC	Sister chromatid biorientation →	+0.156	+0.813	<.001	<.001	3	11
LUNG_SCLC	Post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery →	+0.127	+1.303	.001	<.001	3	11
KIDNEY	Protein desumoylation →	+0.112	+0.745	.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,203 associations by consensus.

Ribosomal protein import into nucleus by CDC16 expression — BREAST

Explore this box plot interactively →