CDC14B

Across TCGA patient cohorts, CDC14B RNA expression is significantly associated with the protein abundance of many other proteins, with 21,768 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CDC14B-associated proteins across cancer lineages are BRD3, SPIN1, and THEMIS2. Each is linked with CDC14B in more than 6 cancer types. Because this analysis shows association rather than direction, both CDC14B-to-partner and partner-to-CDC14B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDC14B versus BRD3 in PDAC, with a Pearson correlation of 0.55.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC14B→partner) and Y-score (partner→CDC14B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	BRD3 →	+0.310	+0.393	<.001	<.001	3	7
LSCC	SPIN1 →	+0.335	+0.445	<.001	<.001	3	6
UCEC	THEMIS2 →	-0.449	-0.489	.002	.006	3	6
GBM	PHC3 →	+0.456	+0.433	<.001	.005	3	6
HNSC	NRBF2 →	-0.377	-0.755	<.001	<.001	3	6
CCRCC	CEBPB →	-0.366	-0.501	.003	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,768 associations by consensus.

CDC14B vs BRD3 — PDAC

Explore this scatter interactively →