CDC14B

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CDC14B protein abundance is significantly associated with the RNA expression of many other genes, with 7,464 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CDC14B-associated genes across cancer lineages are NUPR1, CDCA7, and RBM15. Each is linked with CDC14B in more than 4 cancer types. Because this analysis shows association rather than direction, both CDC14B-to-partner and partner-to-CDC14B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDC14B versus NUPR1 in HNSC, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC14B→partner) and Y-score (partner→CDC14B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCNUPR1 →+1.039+1.008<.001<.00135
BRCACDCA7 →-2.028-0.851<.001<.00133
GBMRBM15 →-0.607-1.231<.001<.00133
GBMUBE2FP3 →-0.840-1.164.001<.00133
BRCAFERMT1 →-1.142-0.644<.001<.00133
GBMRALGPS1 →-0.689-0.649<.001.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,464 associations by consensus.

CDC14B vs NUPR1 — HNSC

Per-sample scatter of CDC14B vs NUPR1 in HNSC (Pearson r = 0.41).

Explore this scatter interactively →

Exploration