CDC123

Across TCGA patient cohorts, CDC123 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,608 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CDC123-associated proteins across cancer lineages are UPF2, LARP4B, and CDK1. Each is linked with CDC123 in more than 8 cancer types. Because this analysis shows association rather than direction, both CDC123-to-partner and partner-to-CDC123 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDC123 versus UPF2 in BRCA, with a Pearson correlation of 0.68.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC123→partner) and Y-score (partner→CDC123) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	UPF2 →	+0.344	+0.692	<.001	<.001	3	9
BRCA	LARP4B →	+0.386	+0.621	<.001	<.001	3	9
BRCA	CDK1 →	+0.820	+0.696	<.001	<.001	3	7
BRCA	DDX50 →	+0.434	+0.788	<.001	<.001	3	7
OV	NUDT5 →	+0.601	+0.384	.003	.007	3	7
BRCA	CUL2 →	+0.284	+0.633	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,608 associations by consensus.

CDC123 vs UPF2 — BRCA

Explore this scatter interactively →