CDC123

Across TCGA patient cohorts, CDC123 protein abundance is significantly associated with the RNA expression of many other genes, with 10,252 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CDC123-associated genes across cancer lineages are FBH1, GTPBP4, and EIF2S2. Each is linked with CDC123 in more than 5 cancer types. Because this analysis shows association rather than direction, both CDC123-to-partner and partner-to-CDC123 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDC123 versus FBH1 in BRCA, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC123→partner) and Y-score (partner→CDC123) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	FBH1 →	+0.548	+0.450	<.001	.001	3	6
BRCA	GTPBP4 →	+0.798	+0.454	<.001	<.001	3	6
BRCA	EIF2S2 →	+0.563	+0.521	<.001	<.001	3	5
COAD	POMP →	+0.582	+0.296	<.001	.008	3	5
BRCA	NUDT5 →	+0.593	+0.399	<.001	<.001	3	5
BRCA	CDC20 →	+1.428	+0.418	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,252 associations by consensus.

CDC123 vs FBH1 — BRCA

Explore this scatter interactively →