CDAN1

Across TCGA patient cohorts, CDAN1 mutation is significantly associated with the total protein of many other genes, with 40 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CDAN1-associated genes across cancer lineages are ATM, N-Ras, and ASNS. Each is linked with CDAN1 in more than 3 cancer types. Because this analysis shows association rather than direction, both CDAN1-to-partner and partner-to-CDAN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by CDAN1-low versus CDAN1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDAN1→partner) and Y-score (partner→CDAN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.498	-2.401	<.001	.002	3	4
UCEC	N-Ras →	-0.078	-1.379	.046	.019	3	3
UCEC	ASNS →	+0.280	+1.415	.018	.043	3	3
STAD	Caspase-7-cleavedD198 →	+1.238	+3.000	.001	.036	2	3
STAD	CD31 →	-0.174	-3.000	.031	.036	3	2
COAD	EGFR_pY1173 →	+0.135	+2.849	.009	.034	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 40 associations by consensus.

ATM by CDAN1 expression — UCEC

Explore this box plot interactively →