CDAN1

Across TCGA cell cohorts, CDAN1 mutation is significantly associated with the RNA expression of many other genes, with 266 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CDAN1-associated genes across cancer lineages are PRKACG, F9, and RPL10L. Each is linked with CDAN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDAN1-to-partner and partner-to-CDAN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRKACG grouped by CDAN1-low versus CDAN1-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDAN1→partner) and Y-score (partner→CDAN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	PRKACG →	+0.027	+4.169	<.001	.008	3	2
BLOOD_Lymphoma	F9 →	+0.040	+4.523	<.001	.004	3	1
BLOOD_Lymphoma	RPL10L →	+0.202	+4.191	<.001	.007	3	1
BLOOD_Lymphoma	KRTAP4-4 →	+0.024	+4.643	<.001	.005	3	1
BLOOD_Lymphoma	ZNF804B →	+0.013	+4.350	<.001	.005	3	1
BLOOD_Lymphoma	TFDP3 →	+0.243	+4.523	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 266 associations by consensus.

PRKACG by CDAN1 expression — CNS

Explore this box plot interactively →