CD99L2

Across TCGA patient cohorts, CD99L2 mutation is significantly associated with the total protein of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD99L2-associated genes across cancer lineages are MEK1, 14-3-3_beta, and ERK2. Each is linked with CD99L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD99L2-to-partner and partner-to-CD99L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MEK1 grouped by CD99L2-low versus CD99L2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD99L2→partner) and Y-score (partner→CD99L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MEK1 →	+0.384	+2.415	.009	.003	3	2
UCEC	14-3-3_beta →	-0.116	-2.432	.004	.018	3	1
UCEC	ERK2 →	+0.205	+3.459	.008	.005	3	1
UCEC	p62 Lck ligand →	+0.400	+2.817	.002	.001	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

MEK1 by CD99L2 expression — UCEC

Explore this box plot interactively →