CD99

Across TCGA patient cohorts, CD99 mutation is significantly associated with the RNA expression of many other genes, with 490 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD99-associated genes across cancer lineages are PTP4A1P7, RNU6-380P, and HINT1P2. Each is linked with CD99 in more than 2 cancer types. Because this analysis shows association rather than direction, both CD99-to-partner and partner-to-CD99 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PTP4A1P7 grouped by CD99-low versus CD99-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD99→partner) and Y-score (partner→CD99) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PTP4A1P7 →	+0.278	+2.393	<.001	.005	3	3
UCEC	RNU6-380P →	+0.170	+4.148	<.001	.006	3	2
LUSC	HINT1P2 →	+0.209	+4.984	.002	.009	3	2
BLCA	LIMS3 →	+0.025	+4.497	<.001	.009	3	1
BLCA	MIR4423 →	+0.548	+5.018	<.001	.004	3	1
BRCA	TAF9P1 →	+0.104	+8.471	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 490 associations by consensus.

PTP4A1P7 by CD99 expression — UCEC

Explore this box plot interactively →