CD99

Across TCGA patient cohorts, CD99 mutation is significantly associated with the total protein of many other genes, with 11 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD99-associated genes across cancer lineages are JNK_pT183_Y185, p62 Lck ligand, and p70-S6K_pT389. Each is linked with CD99 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD99-to-partner and partner-to-CD99 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, JNK_pT183_Y185 grouped by CD99-low versus CD99-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD99→partner) and Y-score (partner→CD99) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JNK_pT183_Y185 →	-0.225	-3.156	.015	.020	3	1
UCEC	p62 Lck ligand →	+0.556	+3.009	.001	.019	3	1
UCEC	p70-S6K_pT389 →	-0.266	-3.160	.010	.019	2	2
UCEC	PCNA →	+0.340	+3.169	.004	.020	2	2
UCEC	Annexin-1 →	+1.108	+3.019	<.001	.019	3	1
UCEC	C-Raf →	+0.206	+3.000	.008	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

JNK_pT183_Y185 by CD99 expression — UCEC

Explore this box plot interactively →