CD96

Across TCGA patient cohorts, CD96 mutation is significantly associated with the total protein of many other genes, with 39 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD96-associated genes across cancer lineages are mTOR_pS2448, TFRC, and PCNA. Each is linked with CD96 in more than 2 cancer types. Because this analysis shows association rather than direction, both CD96-to-partner and partner-to-CD96 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mTOR_pS2448 grouped by CD96-low versus CD96-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD96→partner) and Y-score (partner→CD96) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	mTOR_pS2448 →	-0.143	-2.308	.002	.005	3	3
UCEC	TFRC →	+0.346	+1.584	.038	.034	3	3
LUAD	PCNA →	+0.221	+2.820	.026	.035	2	3
LUAD	cIAP →	+0.135	+2.819	.044	.035	3	2
COAD	14-3-3_beta →	-0.213	-2.974	.044	.036	3	2
UCEC	EGFR_pY1068 →	-0.165	-1.353	.037	.015	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

mTOR_pS2448 by CD96 expression — UCEC

Explore this box plot interactively →