CD96

Across TCGA cell cohorts, CD96 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,700 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CD96-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Regulation of protein localization to mitochondrion, and Spliceosomal complex assembly. Each is linked with CD96 in more than 7 cancer types. Because this analysis shows association rather than direction, both CD96-to-partner and partner-to-CD96 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by CD96-low versus CD96-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CD96→partner) and Y-score (partner→CD96) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Negative regulation of myoblast fusion →	+0.074	+0.382	<.001	.003	3	7
BLOOD_Leukemia	Regulation of protein localization to mitochondrion →	+0.076	+2.285	<.001	.001	2	8
LUNG_NSCLC_LUSC	Spliceosomal complex assembly →	+0.068	+0.489	<.001	<.001	3	7
LARGE_INTESTINE	Positive regulation of intracellular transport →	+0.055	+0.221	.003	.007	2	8
LARGE_INTESTINE	Regulation of intracellular protein transport →	+0.062	+0.405	<.001	.005	3	7
STOMACH	Protein stabilization →	+0.072	+0.643	<.001	.003	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,700 associations by consensus.

Negative regulation of myoblast fusion by CD96 expression — LUNG_NSCLC_LUSC

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