CD96

Across TCGA cell cohorts, CD96 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CD96-associated genes across cancer lineages are AUH, ACER1, and OR10W1. Each is linked with CD96 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD96-to-partner and partner-to-CD96 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AUH grouped by CD96-low versus CD96-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD96→partner) and Y-score (partner→CD96) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	AUH →	+0.617	+3.064	.002	.009	3	1
LARGE_INTESTINE	ACER1 →	+0.067	+2.560	.005	.009	3	1
LARGE_INTESTINE	OR10W1 →	+0.010	+2.977	<.001	.006	3	1
LARGE_INTESTINE	OR10Q1 →	+0.086	+2.920	.001	.001	3	1
LARGE_INTESTINE	ANKRD63 →	+0.287	+3.893	<.001	<.001	3	1
SKIN	CFHR5 →	+0.006	+4.022	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

AUH by CD96 expression — LARGE_INTESTINE

Explore this box plot interactively →