CD9

Across TCGA patient cohorts, CD9 mutation is significantly associated with the total protein of many other genes, with 17 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD9-associated genes across cancer lineages are JNK_pT183_Y185, mTOR_pS2448, and Akt. Each is linked with CD9 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD9-to-partner and partner-to-CD9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, JNK_pT183_Y185 grouped by CD9-low versus CD9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD9→partner) and Y-score (partner→CD9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JNK_pT183_Y185 →	-0.170	-2.571	.030	.011	3	1
UCEC	mTOR_pS2448 →	-0.166	-2.986	.017	.035	3	1
UCEC	Akt →	-0.266	-3.159	.012	.019	3	1
UCEC	p62 Lck ligand →	+0.556	+3.321	<.001	.009	3	1
UCEC	Shc_pY317 →	-0.207	-3.321	.003	.010	3	1
UCEC	STAT3_pY705 →	-0.408	-2.584	<.001	.011	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

JNK_pT183_Y185 by CD9 expression — UCEC

Explore this box plot interactively →