CD8A

Across TCGA patient cohorts, CD8A RNA expression is significantly associated with the protein abundance of many other proteins, with 15,092 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CD8A-associated proteins across cancer lineages are ADA2, CD48, and CORO1A. Each is linked with CD8A in more than 9 cancer types. Because this analysis shows association rather than direction, both CD8A-to-partner and partner-to-CD8A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CD8A versus ADA2 in CCRCC, with a Pearson correlation of 0.62.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CD8A→partner) and Y-score (partner→CD8A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	ADA2 →	+0.583	+1.235	<.001	<.001	3	10
OV	CD48 →	+1.025	+1.424	<.001	<.001	3	10
OV	CORO1A →	+0.666	+1.241	<.001	<.001	3	10
UCEC	DEF6 →	+0.542	+1.246	<.001	<.001	3	10
LSCC	DOCK10 →	+0.507	+0.990	<.001	<.001	3	10
OV	DOCK2 →	+0.658	+1.506	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,092 associations by consensus.

CD8A vs ADA2 — CCRCC

Explore this scatter interactively →