CD84

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CD84 mutation is significantly associated with the RNA expression of many other genes, with 1,033 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD84-associated genes across cancer lineages are HSPA8P17, LINC01751, and MIR4760. Each is linked with CD84 in more than 2 cancer types. Because this analysis shows association rather than direction, both CD84-to-partner and partner-to-CD84 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HSPA8P17 grouped by CD84-low versus CD84-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD84→partner) and Y-score (partner→CD84) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCHSPA8P17 →+0.028+5.468<.001.00233
SKCMLINC01751 →+0.005+2.990<.001.00632
SKCMMIR4760 →+0.071+3.769<.001.00732
SKCMMIR2681 →+0.054+3.769<.001.00732
HNSCEGFLAM-AS3 →+0.119+5.221<.001.00332
LUSCCINP →+0.517+3.477<.001.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,033 associations by consensus.

HSPA8P17 by CD84 expression — HNSC

Box plot of HSPA8P17 in CD84-low vs CD84-high samples in HNSC.

Explore this box plot interactively →

Exploration