CD84

Across TCGA cell cohorts, CD84 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CD84-associated genes across cancer lineages are KCNK18, PRSS58, and DEFB125. Each is linked with CD84 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD84-to-partner and partner-to-CD84 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KCNK18 grouped by CD84-low versus CD84-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD84→partner) and Y-score (partner→CD84) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	KCNK18 →	+0.019	+5.000	<.001	.006	3	1
PANCREAS	PRSS58 →	+0.092	+5.000	<.001	.006	3	1
BLOOD_Lymphoma	DEFB125 →	+0.032	+5.643	<.001	.002	3	1
BLOOD_Lymphoma	CT47A6 →	+0.103	+5.643	<.001	.002	3	1
BLOOD_Lymphoma	USP17L4 →	+0.006	+5.209	.006	.005	3	1
LARGE_INTESTINE	CASP12 →	+0.031	+3.684	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

KCNK18 by CD84 expression — PANCREAS

Explore this box plot interactively →