CD83

Across TCGA patient cohorts, CD83 protein abundance is significantly associated with the RNA expression of many other genes, with 4,153 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CD83-associated genes across cancer lineages are TLR8, IGLJ3, and SNX22. Each is linked with CD83 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD83-to-partner and partner-to-CD83 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CD83 versus TLR8 in BRCA, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD83→partner) and Y-score (partner→CD83) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TLR8 →	+0.773	+0.826	.009	.009	3	2
BRCA	IGLJ3 →	+2.953	+0.846	.005	.006	3	2
CCRCC	SNX22 →	+0.545	+0.429	.008	.001	3	2
LSCC	WDHD1 →	-0.603	-0.414	.004	.004	3	2
CCRCC	PFN2 →	-1.278	-0.486	.003	.001	3	2
LSCC	CDC45 →	-0.590	-0.400	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,153 associations by consensus.

CD83 vs TLR8 — BRCA

Explore this scatter interactively →