CD83

Across TCGA patient cohorts, CD83 mutation is significantly associated with the RNA expression of many other genes, with 228 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD83-associated genes across cancer lineages are RNA5SP436, YTHDF3-AS1, and MICE. Each is linked with CD83 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD83-to-partner and partner-to-CD83 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP436 grouped by CD83-low versus CD83-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD83→partner) and Y-score (partner→CD83) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP436 →	+0.401	+2.937	<.001	.009	3	2
UCEC	YTHDF3-AS1 →	+0.753	+3.354	<.001	.005	3	1
UCEC	MICE →	+0.414	+2.818	<.001	.002	3	1
UCEC	PRAG1 →	+0.721	+3.354	.008	.005	3	1
UCEC	UHRF1 →	+0.877	+2.711	.002	.003	3	1
LUAD	RNU6-361P →	+0.463	+7.930	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 228 associations by consensus.

RNA5SP436 by CD83 expression — UCEC

Explore this box plot interactively →