CD83

Across TCGA cell cohorts, CD83 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,309 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CD83-associated GO terms across cancer lineages are Negative regulation of RNA export from nucleus, DNA-templated transcription initiation, and Mitotic spindle midzone assembly. Each is linked with CD83 in more than 11 cancer types. Because this analysis shows association rather than direction, both CD83-to-partner and partner-to-CD83 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of RNA export from nucleus grouped by CD83-low versus CD83-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CD83→partner) and Y-score (partner→CD83) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Negative regulation of RNA export from nucleus →	+0.150	+1.805	.001	<.001	3	12
SOFT_TISSUE	DNA-templated transcription initiation →	+0.058	+1.059	<.001	.004	3	11
PANCREAS	Mitotic spindle midzone assembly →	+0.185	+1.099	<.001	.002	3	11
BREAST	Positive regulation of mitotic cell cycle phase transition →	+0.103	+1.791	<.001	<.001	3	11
PANCREAS	Mitotic spindle elongation →	+0.185	+1.099	<.001	.002	3	11
PANCREAS	Cell cycle checkpoint signaling →	+0.063	+1.419	.005	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,309 associations by consensus.

Negative regulation of RNA export from nucleus by CD83 expression — OESOPHAGUS

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