CD80

Across TCGA patient cohorts, CD80 protein abundance is significantly associated with the RNA expression of many other genes, with 5,010 significant associations in total. COAD shows the largest number of these associations.

The most reproducible CD80-associated genes across cancer lineages are CHKB, MCM5, and FOXRED2. Each is linked with CD80 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD80-to-partner and partner-to-CD80 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CD80 versus CHKB in LUAD, with a Pearson correlation of 0.80.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD80→partner) and Y-score (partner→CD80) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CHKB →	+0.651	+0.416	.001	.002	3	1
LUAD	MCM5 →	+1.187	+0.416	<.001	.002	3	1
LUAD	FOXRED2 →	+1.480	+0.580	.001	.005	3	1
LUAD	MTHFD1 →	+1.079	+0.476	.003	.006	3	1
LUAD	RBBP8 →	+1.576	+0.466	.006	.006	3	1
LUAD	ACOD1 →	+0.815	+0.553	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,010 associations by consensus.

CD80 vs CHKB — LUAD

Explore this scatter interactively →