CD80

Across TCGA patient cohorts, CD80 mutation is significantly associated with the RNA expression of many other genes, with 873 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD80-associated genes across cancer lineages are THRAP3P2, CMC4, and RPL34P19. Each is linked with CD80 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD80-to-partner and partner-to-CD80 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, THRAP3P2 grouped by CD80-low versus CD80-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD80→partner) and Y-score (partner→CD80) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	THRAP3P2 →	+0.030	+5.149	<.001	.003	3	2
UCEC	CMC4 →	+0.020	+2.353	.001	.004	3	2
SKCM	RPL34P19 →	+0.141	+2.796	<.001	.004	3	2
LIHC	RNA5SP519 →	+0.271	+5.676	<.001	.001	3	2
SKCM	TEX29 →	+1.003	+3.233	<.001	.008	3	2
UCEC	DOLPP1 →	+0.427	+2.364	.009	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 873 associations by consensus.

THRAP3P2 by CD80 expression — LIHC

Explore this box plot interactively →