CD80

Across TCGA cell cohorts, CD80 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CD80-associated genes across cancer lineages are TECRL, CD300H, and MMP26. Each is linked with CD80 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD80-to-partner and partner-to-CD80 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TECRL grouped by CD80-low versus CD80-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD80→partner) and Y-score (partner→CD80) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TECRL →	+0.026	+4.977	<.001	.007	3	1
LARGE_INTESTINE	CD300H →	+0.045	+5.415	<.001	.004	3	1
STOMACH	MMP26 →	+0.673	+5.285	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

TECRL by CD80 expression — LARGE_INTESTINE

Explore this box plot interactively →