CD79B

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CD79B mutation is significantly associated with the RNA expression of many other genes, with 815 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD79B-associated genes across cancer lineages are ZMYND10-AS1, CPVL-AS1, and RBX1P1. Each is linked with CD79B in more than 2 cancer types. Because this analysis shows association rather than direction, both CD79B-to-partner and partner-to-CD79B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZMYND10-AS1 grouped by CD79B-low versus CD79B-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD79B→partner) and Y-score (partner→CD79B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMZMYND10-AS1 →+0.175+4.253<.001<.00133
DLBCCPVL-AS1 →+0.135+4.357.002.00432
BLCARBX1P1 →+0.129+7.640<.001.00932
SKCMRNU6-1216P →+0.254+3.533.002.00732
CESCNF1P6 →+0.096+6.342<.001.00132
LUADLINC02222 →+0.073+6.087<.001.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 815 associations by consensus.

ZMYND10-AS1 by CD79B expression — SKCM

Box plot of ZMYND10-AS1 in CD79B-low vs CD79B-high samples in SKCM.

Explore this box plot interactively →

Exploration