CD79A

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CD79A mutation is significantly associated with the total protein of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD79A-associated genes across cancer lineages are GATA6, JNK2, and N-Ras. Each is linked with CD79A in more than 1 cancer types. Because this analysis shows association rather than direction, both CD79A-to-partner and partner-to-CD79A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GATA6 grouped by CD79A-low versus CD79A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD79A→partner) and Y-score (partner→CD79A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECGATA6 →-0.247-3.000.003.03531
UCECJNK2 →+0.236+2.817.030.03631
UCECN-Ras →-0.132-3.156.044.02031
UCECCaspase-8 →-0.316-3.143.022.01831
UCEC14-3-3_beta →-0.126-3.156.022.02021
UCECCaspase-7-cleavedD198 →+0.889+3.169.006.02011
Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

GATA6 by CD79A expression — UCEC

Box plot of GATA6 in CD79A-low vs CD79A-high samples in UCEC.

Explore this box plot interactively →

Exploration