CD79A

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CD79A mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible CD79A-associated genes across cancer lineages are SLC10A2, DHRS7C, and OR10J1. Each is linked with CD79A in more than 1 cancer types. Because this analysis shows association rather than direction, both CD79A-to-partner and partner-to-CD79A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC10A2 grouped by CD79A-low versus CD79A-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD79A→partner) and Y-score (partner→CD79A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKINSLC10A2 →+0.005+5.022<.001.00231
SKINDHRS7C →+0.044+4.415<.001.00731
SKINOR10J1 →+0.021+5.217<.001<.00131
OVARYNLRP2B →+0.055+4.807<.001<.00131
OVARYOR12D2 →+0.033+3.700.001.00531
OVARYPAX7 →+0.776+4.044<.001.00321
Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

SLC10A2 by CD79A expression — SKIN

Box plot of SLC10A2 in CD79A-low vs CD79A-high samples in SKIN.

Explore this box plot interactively →

Exploration