CD72

Across TCGA patient cohorts, CD72 mutation is significantly associated with the total protein of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD72-associated genes across cancer lineages are Rab25, EGFR_pY1068, and A-Raf_pS299. Each is linked with CD72 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD72-to-partner and partner-to-CD72 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Rab25 grouped by CD72-low versus CD72-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD72→partner) and Y-score (partner→CD72) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Rab25 →	-0.380	-2.999	.011	.035	3	2
UCEC	EGFR_pY1068 →	-0.317	-2.700	.005	.006	3	1
UCEC	A-Raf_pS299 →	-0.139	-2.999	.010	.035	3	1
UCEC	JNK2 →	+0.234	+2.000	.008	.032	3	1
UCEC	Ku80 →	+0.240	+3.820	.024	<.001	3	1
UCEC	Mre11 →	-0.099	-2.000	.010	.032	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

Rab25 by CD72 expression — UCEC

Explore this box plot interactively →