CD72

Across TCGA cell cohorts, CD72 mutation is significantly associated with the RNA expression of many other genes, with 23 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CD72-associated genes across cancer lineages are OR4M1, C20orf85, and CST8. Each is linked with CD72 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD72-to-partner and partner-to-CD72 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4M1 grouped by CD72-low versus CD72-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD72→partner) and Y-score (partner→CD72) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	OR4M1 →	+0.018	+5.169	.007	.005	3	1
BLOOD_Leukemia	C20orf85 →	+0.033	+4.384	<.001	.006	3	1
BLOOD_Leukemia	CST8 →	+0.037	+4.384	<.001	.006	3	1
BLOOD_Leukemia	BTBD16 →	+0.094	+3.959	<.001	.005	3	1
BLOOD_Leukemia	CYP39A1 →	+0.181	+3.769	<.001	.008	3	1
BLOOD_Leukemia	OR10K2 →	+0.043	+3.705	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

OR4M1 by CD72 expression — BREAST

Explore this box plot interactively →