CD7

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, CD7 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated CD7 data layer compared with 28 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher CD7 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated CD7 expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

LUAD and HNSC are the cancer types where CD7 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUADDFSTertileAll0.7990.474.00321view →
HNSCDFSTertileAll0.9131.000.0187view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

CD7–LUAD (DFS)

Kaplan–Meier survival curve for CD7 mass-spec protein-high vs -low samples in LUAD.

Open the LUAD breakdown →

Exploration