CD7

Across TCGA patient cohorts, CD7 mutation is significantly associated with the RNA expression of many other genes, with 200 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD7-associated genes across cancer lineages are MIR6074, MIR513B, and RNU6-241P. Each is linked with CD7 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD7-to-partner and partner-to-CD7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6074 grouped by CD7-low versus CD7-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD7→partner) and Y-score (partner→CD7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR6074 →	+0.170	+4.219	<.001	.006	3	2
UCEC	MIR513B →	+0.351	+3.299	<.001	.001	3	2
UCEC	RNU6-241P →	+0.238	+3.885	<.001	.008	3	2
UCEC	RNU7-74P →	+0.314	+3.153	<.001	.006	3	2
UCEC	RN7SL649P →	+0.154	+2.567	.001	.008	3	2
SKCM	RNU6-306P →	+0.171	+3.372	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 200 associations by consensus.

MIR6074 by CD7 expression — SKCM

Explore this box plot interactively →