CD7

Across TCGA patient cohorts, CD7 mutation is significantly associated with the total protein of many other genes, with 10 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD7-associated genes across cancer lineages are N-Cadherin, PDK1_pS241, and PEA-15_pS116. Each is linked with CD7 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD7-to-partner and partner-to-CD7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, N-Cadherin grouped by CD7-low versus CD7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD7→partner) and Y-score (partner→CD7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	N-Cadherin →	-0.337	-2.990	.002	.036	3	1
UCEC	PDK1_pS241 →	+0.188	+2.183	.036	.035	3	1
UCEC	PEA-15_pS116 →	-0.458	-3.000	.012	.036	3	1
UCEC	Syk →	+0.406	+3.335	.038	.005	3	1
UCEC	Bcl-xL →	-0.205	-3.321	.014	.010	3	1
UCEC	cIAP →	+0.148	+2.196	.040	.034	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

N-Cadherin by CD7 expression — UCEC

Explore this box plot interactively →