CD69

Across TCGA patient cohorts, CD69 mutation is significantly associated with the RNA expression of many other genes, with 2,277 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD69-associated genes across cancer lineages are NOL12, RPL23AP84, and H2AZ1. Each is linked with CD69 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD69-to-partner and partner-to-CD69 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NOL12 grouped by CD69-low versus CD69-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD69→partner) and Y-score (partner→CD69) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NOL12 →	+0.343	+1.797	.001	.008	3	2
SKCM	RPL23AP84 →	+0.072	+3.186	<.001	.009	3	2
UCEC	H2AZ1 →	+0.714	+2.202	<.001	.001	3	2
UCEC	CIDECP1 →	+0.508	+2.716	<.001	<.001	3	2
UCEC	C19orf54 →	+0.490	+2.455	<.001	.001	3	2
UCEC	MFSD14C →	+0.622	+2.695	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,277 associations by consensus.

NOL12 by CD69 expression — UCEC

Explore this box plot interactively →