CD69

Across TCGA patient cohorts, CD69 mutation is significantly associated with the total protein of many other genes, with 21 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD69-associated genes across cancer lineages are A-Raf_pS299, FOXO3a_pS318_S321, and FOXO3a. Each is linked with CD69 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD69-to-partner and partner-to-CD69 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, A-Raf_pS299 grouped by CD69-low versus CD69-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD69→partner) and Y-score (partner→CD69) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	A-Raf_pS299 →	-0.151	-2.459	.002	.019	3	1
UCEC	FOXO3a_pS318_S321 →	-0.134	-2.312	.009	.034	3	1
UCEC	FOXO3a →	-0.104	-3.429	.013	.005	3	1
UCEC	JNK_pT183_Y185 →	-0.149	-1.794	.031	.027	3	1
UCEC	Mre11 →	-0.075	-1.807	.034	.027	3	1
UCEC	mTOR_pS2448 →	-0.140	-1.807	.022	.027	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

A-Raf_pS299 by CD69 expression — UCEC

Explore this box plot interactively →