CD69

Across TCGA cell cohorts, CD69 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,245 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CD69-associated GO terms across cancer lineages are Response to type I interferon, Cellular response to type I interferon, and Regulation of viral budding via host ESCRT complex. Each is linked with CD69 in more than 6 cancer types. Because this analysis shows association rather than direction, both CD69-to-partner and partner-to-CD69 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to type I interferon grouped by CD69-low versus CD69-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CD69→partner) and Y-score (partner→CD69) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Response to type I interferon →	+0.040	+1.441	.002	.001	3	6
BONE	Cellular response to type I interferon →	+0.073	+0.068	<.001	.001	2	7
UPPER_AERODIGESTIVE_TRACT	Regulation of viral budding via host ESCRT complex →	+0.104	+0.374	<.001	.004	3	5
UPPER_AERODIGESTIVE_TRACT	Positive regulation of viral budding via host ESCRT complex →	+0.104	+0.374	<.001	.004	3	5
UPPER_AERODIGESTIVE_TRACT	Cellular component disassembly →	+0.047	+0.517	<.001	.003	3	5
UPPER_AERODIGESTIVE_TRACT	Negative regulation of regulatory T cell differentiation →	+0.135	+0.482	.003	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,245 associations by consensus.

Response to type I interferon by CD69 expression — BLOOD_Leukemia

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