CD69

Across TCGA cell cohorts, CD69 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible CD69-associated genes across cancer lineages are MAGEB4, OR5AU1, and OR4D5. Each is linked with CD69 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD69-to-partner and partner-to-CD69 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAGEB4 grouped by CD69-low versus CD69-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD69→partner) and Y-score (partner→CD69) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	MAGEB4 →	+0.003	+4.078	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR5AU1 →	+0.032	+3.734	<.001	.006	3	1
LUNG_NSCLC_LUAD	OR4D5 →	+0.011	+4.078	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR10G7 →	+0.009	+4.078	<.001	.009	3	1
LUNG_NSCLC_LUAD	LCE2C →	+0.023	+4.078	<.001	.009	3	1
LUNG_NSCLC_LUAD	GLT6D1 →	+0.003	+4.078	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

MAGEB4 by CD69 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →