CD59

Across TCGA patient cohorts, CD59 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,202 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CD59-associated proteins across cancer lineages are AATF, CDK12_S1083, and DDX47. Each is linked with CD59 in more than 5 cancer types. Because this analysis shows association rather than direction, both CD59-to-partner and partner-to-CD59 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CD59 versus AATF in COAD, with a Pearson correlation of -0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CD59→partner) and Y-score (partner→CD59) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	AATF →	-0.465	-0.491	<.001	<.001	3	6
BRCA	CDK12_S1083 →	-0.472	-0.485	.004	.001	3	6
UCEC	DDX47 →	-0.366	-0.666	<.001	<.001	3	6
COAD	EMG1 →	-0.504	-0.393	<.001	.005	3	6
UCEC	GPATCH4_S135 →	-0.643	-0.544	<.001	.003	3	6
LSCC	IMP4 →	-0.273	-0.386	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,202 associations by consensus.

CD59 vs AATF — COAD

Explore this scatter interactively →