CD59

Across TCGA patient cohorts, CD59 protein abundance is significantly associated with the RNA expression of many other genes, with 556 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CD59-associated genes across cancer lineages are FEZF1, TRAJ21, and GAPDHP20. Each is linked with CD59 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD59-to-partner and partner-to-CD59 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CD59 versus FEZF1 in OV, with a Pearson correlation of 0.75.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD59→partner) and Y-score (partner→CD59) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	FEZF1 →	+0.073	+0.635	.007	.001	3	1
OV	TRAJ21 →	+2.760	+0.736	<.001	.001	3	1
OV	GAPDHP20 →	+0.356	+0.709	<.001	.007	3	1
OV	LINC01747 →	+0.086	+0.672	<.001	.003	3	1
OV	RPS25P3 →	+0.510	+0.635	.003	.001	3	1
OV	FABP6-AS1 →	+0.076	+0.635	.006	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 556 associations by consensus.

CD59 vs FEZF1 — OV

Explore this scatter interactively →