CD59

Across TCGA cell cohorts, CD59 protein abundance is significantly associated with the go_rna of many other GO terms, with 2,668 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CD59-associated GO terms across cancer lineages are Negative regulation of wound healing, Intestinal lipid absorption, and Regulation of wound healing. Each is linked with CD59 in more than 9 cancer types. Because this analysis shows association rather than direction, both CD59-to-partner and partner-to-CD59 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of wound healing grouped by CD59-low versus CD59-high in BONE.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CD59→partner) and Y-score (partner→CD59) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of wound healing →	+0.158	+2.589	<.001	<.001	3	10
SOFT_TISSUE	Intestinal lipid absorption →	+0.435	+2.524	.004	.002	3	8
BONE	Regulation of wound healing →	+0.169	+2.408	<.001	.002	2	9
LIVER	Wound healing →	+0.188	+3.270	.001	<.001	3	8
BLOOD_Lymphoma	Regulation of proteolysis →	+0.102	+2.094	<.001	.002	3	8
BREAST	Maintenance of protein location in cell →	+0.101	+1.623	.006	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,668 associations by consensus.

Negative regulation of wound healing by CD59 expression — BONE

Explore this box plot interactively →