CD53

Across TCGA patient cohorts, CD53 RNA expression is significantly associated with the protein abundance of many other proteins, with 24,933 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CD53-associated proteins across cancer lineages are WAS, WIPF1, and STK10. Each is linked with CD53 in more than 9 cancer types. Because this analysis shows association rather than direction, both CD53-to-partner and partner-to-CD53 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CD53 versus WAS in GBM, with a Pearson correlation of 0.88.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CD53→partner) and Y-score (partner→CD53) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	WAS →	+0.819	+1.353	<.001	<.001	3	10
OV	WIPF1 →	+0.532	+1.244	<.001	<.001	3	10
HNSC	STK10 →	+0.557	+1.278	<.001	<.001	3	10
HNSC	STK4 →	+0.524	+1.267	<.001	<.001	3	10
OV	STX11 →	+0.615	+1.070	<.001	<.001	3	10
GBM	TNFAIP8 →	+0.854	+1.188	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 24,933 associations by consensus.

CD53 vs WAS — GBM

Explore this scatter interactively →