CD52

Across TCGA patient cohorts, CD52 mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD52-associated genes across cancer lineages are UGT2B10, RN7SL267P, and RN7SL470P. Each is linked with CD52 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD52-to-partner and partner-to-CD52 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UGT2B10 grouped by CD52-low versus CD52-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD52→partner) and Y-score (partner→CD52) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	UGT2B10 →	+0.368	+3.041	<.001	.008	3	1
SKCM	RN7SL267P →	+0.285	+5.159	<.001	.007	3	1
UCEC	RN7SL470P →	+0.266	+3.109	.006	.007	3	1
UCEC	MIR4752 →	+0.321	+6.744	<.001	<.001	3	1
UCEC	RNU6-208P →	+0.433	+3.409	.005	.003	3	1
UCEC	RNU6-697P →	+0.440	+3.386	.005	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

UGT2B10 by CD52 expression — UCEC

Explore this box plot interactively →