CD5

Across TCGA patient cohorts, CD5 mutation is significantly associated with the immune_cell of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD5-associated genes across cancer lineages are pDC, Neurons, and CD8+ naive T-cells. Each is linked with CD5 in more than 3 cancer types. Because this analysis shows association rather than direction, both CD5-to-partner and partner-to-CD5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, pDC grouped by CD5-low versus CD5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD5→partner) and Y-score (partner→CD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	pDC →	+0.046	+3.032	.020	.018	3	4
SKCM	Neurons →	+0.032	+2.826	.005	.036	3	2
UCEC	CD8+ naive T-cells →	+0.026	+1.850	.020	.015	3	2
UCEC	Erythrocytes →	+0.025	+2.321	.012	.006	3	2
LUSC	Eosinophils →	+0.032	+2.910	.003	.012	3	1
LUSC	Hepatocytes →	+0.011	+2.881	.006	.049	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

pDC by CD5 expression — UCEC

Explore this box plot interactively →