CD5

Across TCGA cell cohorts, CD5 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,523 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CD5-associated GO terms across cancer lineages are Microtubule nucleation, Positive regulation of intracellular protein transport, and Negative regulation of myoblast fusion. Each is linked with CD5 in more than 6 cancer types. Because this analysis shows association rather than direction, both CD5-to-partner and partner-to-CD5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule nucleation grouped by CD5-low versus CD5-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CD5→partner) and Y-score (partner→CD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Microtubule nucleation →	+0.066	+1.581	.002	.005	3	7
PANCREAS	Positive regulation of intracellular protein transport →	+0.065	+0.075	<.001	.006	3	7
PANCREAS	Negative regulation of myoblast fusion →	+0.064	+0.065	.001	.002	3	7
PANCREAS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.089	+0.072	<.001	.003	3	7
SOFT_TISSUE	Glycerolipid biosynthetic process →	+0.028	+0.071	<.001	.002	3	6
SKIN	Vacuole organization →	+0.032	+0.032	.004	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,523 associations by consensus.

Microtubule nucleation by CD5 expression — BLOOD_Leukemia

Explore this box plot interactively →