CD46P1

Across TCGA pan-cancer cohorts, CD46P1 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated CD46P1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher CD46P1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CD46P1 expression acts as an unfavorable survival marker, although some lineages such as LAML and DLBC show a favorable association.

KIRC, UVM, and MESO are the cancer types where CD46P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	III,IV	0.519	0.698	<.001	93	view →
UVM	DFS	Tertile	All	0.126	0.768	<.001	54	view →
MESO	DFS	Tertile	IV	0.119	0.418	<.001	51	view →
THYM	DFS	Tertile	All	0.361	0.837	<.001	33	view →
LAML	DFS	Median	All	0.573	0.351	.002	26	view →
BRCA	OS	Tertile	II,III,IV	0.880	0.926	.009	24	view →
GBM	DFS	Tertile	All	0.108	0.266	<.001	18	view →
DLBC	DFS	Median	All	1.000	0.438	.007	16	view →
LUAD	DFS	Median	IV	0.888	0.525	.005	12	view →
HNSC	OS	Tertile	III,IV	0.808	0.697	.016	12	view →
LIHC	DFS	Tertile	II,III,IV	0.278	0.488	.021	9	view →
PAAD	OS	Median	III,IV	0.629	1.000	.022	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

CD46P1–KIRC (DFS)

Open the KIRC breakdown →