CD46

Across TCGA patient cohorts, CD46 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,670 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CD46-associated proteins across cancer lineages are BROX, GGPS1, and RCOR3. Each is linked with CD46 in more than 5 cancer types. Because this analysis shows association rather than direction, both CD46-to-partner and partner-to-CD46 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CD46 versus BROX in HNSC, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CD46→partner) and Y-score (partner→CD46) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	BROX →	+0.525	+0.856	<.001	<.001	3	6
COAD	GGPS1 →	+0.339	+0.463	.001	<.001	3	6
HNSC	RCOR3 →	+0.475	+0.811	<.001	<.001	3	5
BRCA	RNPEP →	+0.381	+0.925	<.001	<.001	3	5
UCEC	BPNT1 →	+0.450	+0.744	<.001	<.001	3	5
LUAD	GNPAT →	+0.487	+0.622	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,670 associations by consensus.

CD46 vs BROX — HNSC

Explore this scatter interactively →