CD46

Across TCGA patient cohorts, CD46 protein abundance is significantly associated with the RNA expression of many other genes, with 11,707 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CD46-associated genes across cancer lineages are CHST11, GLT8D2, and PDLIM2. Each is linked with CD46 in more than 5 cancer types. Because this analysis shows association rather than direction, both CD46-to-partner and partner-to-CD46 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CD46 versus CHST11 in COAD, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD46→partner) and Y-score (partner→CD46) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CHST11 →	-0.794	-0.530	<.001	<.001	3	6
OV	GLT8D2 →	-1.037	-0.454	<.001	<.001	3	5
COAD	PDLIM2 →	-0.421	-0.492	<.001	<.001	3	5
COAD	GYPC →	-0.687	-0.400	<.001	<.001	3	5
LSCC	FKBP10 →	-1.013	-0.343	<.001	<.001	3	5
OV	EMP3 →	-0.669	-0.411	.006	.003	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,707 associations by consensus.

CD46 vs CHST11 — COAD

Explore this scatter interactively →